Signum Biosciences Overview 

By 13/04/2017Uncategorized

Our science applies the rigor of drug development to the development of consumer products. We see the human element in all the science especially the person at the other end of the process. What we do isn’t just science for the sake of science. It has a very real, direct effect on people’s lives. We share these products with our families and for that reason, we take the development of consumer products every bit as seriously as we do prescription products. We set the bar very high in everything we do from the moment we set out, to the moment of discovery, to the moment it leaves our hands for yours.

What We Do
At Signum Biosciences, we’re curious, restless and we’re never satisfied with “it can’t be done.” As scientists, we simply refuse to believe that there’s anything that can’t be done. So we set ourselves tough tasks. Alzheimer’s, Parkinson’s, Rosacea, Ageing, Inflammation and we set out, not for the easy answers, but for the difficult ones. We believe, in those difficult places, the greatest discoveries are made.

How We Started
It could be said, rightly, that Signum Biosciences CEO Maxwell Stock grew up in the lab, a child of research science. Following his father, Dr. Jeffry Stock, Chairman of Signum Biosciences and Professor and Independent Investigator at Princeton University to work, Max’s earliest memories are of the chemicals being studied, the tools being used, the conversations around the dinner table of cells, biochemistry, micro-organisms and bacteria. A fascination that never abated, through a major in molecular biology at the University of Colorado, to work in the science industry, to 3 years of bench work generating data to the formation, with his father, of Signum Biosciences. The close relationship of this father / son team, their shared entrepreneurial spirit, and their belief that great science must go from the bench all the way to the shelf where it can help people in their real lives with real solutions to real problems, has made Signum Biosciences what it is today; a biotechnology company with a reputation for great science, operating in the lab and in the lives of real people. Pursuing, in everything we do, the science of staying healthy.

SIG-1273 is a multi-functional novel compound designed to address the many causes of skin ageing which can be found in Neora’s Day & Night Creams. In addition to its anti-inflammatory properties that target chronic inflammation by blocking the pro inflammatory effects of UVB, UVA, bacteria, chemical irritants, pollution, etc.., SIG-1273 also has anti-oxidant properties, protects collagen and boosts the skin’s repair mechanism. Thus, SIG-1273 targets the causes of skin ageing, not just the symptoms.

How was it developed? What makes this ingredient so impactful and unique? 
SIG-1273 was developed through our research with Isoprenylcysteine molecules IPC’s. It targets the cause of ageing at a cellular level by acting as a powerful anti-oxidant, reducing oxidative stress and free radial damage from sun, pollution, and other environmental factors. It protects against collagen breakdown, mimics and boosts the skin’s natural age-fighting mechanisms as well as blocks UVb induced IL-6, a pro-inflammatory cytokine.

How it developed and what was makes it so impactful? SIG-1191 was also developed through our research with Isoprenylcysteine molecules IPC’s. What makes SIG-1191 so impactful and unique is its ability to utilise Aquaporin-3, the major aquaporin found in the skin. AQP3’s role in the skin is to increase glycerol and water content which results in increased hydration, moisturisation, barrier recovery and wound healing. It also increases Heme oxygenase 1 (HO-1) expression which is responsible for breaking down HEME. HEME accumulation underneath the eyes is one of the main causes of dark circles beneath the eye.  It delivers an immediate reduction in the appearance of fine lines and wrinkles, fights the appearance of dark circles and firms and brightens the appearance of the eye area. It is ideal for all skin types because it matches your skin’s natural pH level, ensuring optimal skin health. SIG-1191 can be found in can be found in Neora’s Age IQ Eye Serum and also in our Eye-V Moisture Boost Hydrogel Patches.

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